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fusobacterium nucleatum f n  (Kamada)

 
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    Kamada fusobacterium nucleatum f n
    Fusobacterium Nucleatum F N, supplied by Kamada, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/f+nucleatum/fusobacterium+nucleatum+oral/pm42242180-39-39-31
    Average 86 stars, based on 1 article reviews
    fusobacterium nucleatum f n - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    Bacteria:

    Article Title: Bacterial extracellular vesicles in the oral-gut axis: Roles in periodontitis and inflammatory bowel disease.
    Article Snippet: The oral-gut axis links the oral and gut microbiomes, both anatomically and functionally, and its dysregulation is implicated in periodontitis and inflammatory bowel disease (IBD).. Bacterial extracellular vesicles (BEVs), nanosized particles (20–250 nm) released by diverse microbes, serve as key mediators of inter-organismal communication along this axis.. Carrying virulence factors, nucleic acids, and immunomodulators, BEVs influence microbial ecology and host immunity.



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    f nucleatum subsp nucleatum strain vpi 4355  (ATCC)
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    A) Alpha diversity (Observed richness, Shannon index) in tumor vs. non-tumor samples (n = 32, 31), and tumors stratified by location (right, n = 16; left, n = 16) or stage (early, n = 22; late, n = 10). B) Differential abundance analysis at the species level comparing tumor vs non-tumor (left), right vs left tumor (middle), and early vs late stage tumor (right). Volcano plots highlight significantly enriched taxa (FDR < 0.05). C) Phylum-level taxonomic composition in tumor and non-tumor tissues, showing enrichment of Fusobacteriota in tumors. D) Genus-level composition of tumors stratified by <t>Fusobacterium</t> <t>nucleatum</t> detection by qPCR (positive vs. negative). E) Top species enriched in tumors from African (AFRg) and European (EURg) ancestry patients (n = 68, WGS); dot size reflects significance (–log10 FDR); colors denote ancestry specificity (red = AFR only, purple = shared). F) Oral-origin taxa significantly enriched in tumors based on presence/absence data and annotation using the Human Oral Microbiome Database (HOMD v16.01). Bar length indicates log2 odds ratio of presence in tumor vs non-tumor (Fisher’s exact test). 16S rRNA sequencing was performed in a sub-cohort of 32 patients (A–D), and WGS in 68 patients (E–F) from the P-1000 cohort.
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    Image Search Results


    Relative expression levels of SMS, PAH, KYNU, ACAT1, PLD2, and ALDH2 in HCT116 colorectal cancer cells following infection with Porphyromonas gingivalis (PG) or Fusobacterium nucleatum (FN) for 6 h and 24 h. Gene expression was quantified by qRT-PCR and expressed as the fold change (2 −ΔΔCt ) relative to uninfected controls. PG predominantly suppressed metabolic gene expression, whereas FN induced differential responses, including increasing the expression of ACAT1, PLD2, and KYNU at 6 h. ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001.

    Journal: Journal of Taibah University Medical Sciences

    Article Title: Metabolic effects of periodontal pathogens Fusobacterium nucleatum and Porphyromonas gingivalis in colorectal cancer cells

    doi: 10.1016/j.jtumed.2026.09.002

    Figure Lengend Snippet: Relative expression levels of SMS, PAH, KYNU, ACAT1, PLD2, and ALDH2 in HCT116 colorectal cancer cells following infection with Porphyromonas gingivalis (PG) or Fusobacterium nucleatum (FN) for 6 h and 24 h. Gene expression was quantified by qRT-PCR and expressed as the fold change (2 −ΔΔCt ) relative to uninfected controls. PG predominantly suppressed metabolic gene expression, whereas FN induced differential responses, including increasing the expression of ACAT1, PLD2, and KYNU at 6 h. ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001.

    Article Snippet: The bacterial strains P. gingivalis ATCC 53977 and F. nucleatum subsp. nucleatum ATCC 25586 were cultured anaerobically in brain heart infusion (BHI) broth supplemented with hemin (5 mg/mL) and menadione (5 mg/mL) (Himedia, India).

    Techniques: Expressing, Infection, Gene Expression, Quantitative RT-PCR

    A) Alpha diversity (Observed richness, Shannon index) in tumor vs. non-tumor samples (n = 32, 31), and tumors stratified by location (right, n = 16; left, n = 16) or stage (early, n = 22; late, n = 10). B) Differential abundance analysis at the species level comparing tumor vs non-tumor (left), right vs left tumor (middle), and early vs late stage tumor (right). Volcano plots highlight significantly enriched taxa (FDR < 0.05). C) Phylum-level taxonomic composition in tumor and non-tumor tissues, showing enrichment of Fusobacteriota in tumors. D) Genus-level composition of tumors stratified by Fusobacterium nucleatum detection by qPCR (positive vs. negative). E) Top species enriched in tumors from African (AFRg) and European (EURg) ancestry patients (n = 68, WGS); dot size reflects significance (–log10 FDR); colors denote ancestry specificity (red = AFR only, purple = shared). F) Oral-origin taxa significantly enriched in tumors based on presence/absence data and annotation using the Human Oral Microbiome Database (HOMD v16.01). Bar length indicates log2 odds ratio of presence in tumor vs non-tumor (Fisher’s exact test). 16S rRNA sequencing was performed in a sub-cohort of 32 patients (A–D), and WGS in 68 patients (E–F) from the P-1000 cohort.

    Journal: medRxiv

    Article Title: Integrative Genomic, Transcriptomic, and Microbiome Profiles of Colon Cancer by Ancestry Provide Insights into Molecular Distinctions

    doi: 10.64898/2026.03.25.26349226

    Figure Lengend Snippet: A) Alpha diversity (Observed richness, Shannon index) in tumor vs. non-tumor samples (n = 32, 31), and tumors stratified by location (right, n = 16; left, n = 16) or stage (early, n = 22; late, n = 10). B) Differential abundance analysis at the species level comparing tumor vs non-tumor (left), right vs left tumor (middle), and early vs late stage tumor (right). Volcano plots highlight significantly enriched taxa (FDR < 0.05). C) Phylum-level taxonomic composition in tumor and non-tumor tissues, showing enrichment of Fusobacteriota in tumors. D) Genus-level composition of tumors stratified by Fusobacterium nucleatum detection by qPCR (positive vs. negative). E) Top species enriched in tumors from African (AFRg) and European (EURg) ancestry patients (n = 68, WGS); dot size reflects significance (–log10 FDR); colors denote ancestry specificity (red = AFR only, purple = shared). F) Oral-origin taxa significantly enriched in tumors based on presence/absence data and annotation using the Human Oral Microbiome Database (HOMD v16.01). Bar length indicates log2 odds ratio of presence in tumor vs non-tumor (Fisher’s exact test). 16S rRNA sequencing was performed in a sub-cohort of 32 patients (A–D), and WGS in 68 patients (E–F) from the P-1000 cohort.

    Article Snippet: For absolute quantification, microbial genomic DNA of F. nucleatum subsp. nucleatum strain VPI 4355 (ATCC # 25586D-5) was used to prepare the standard curve and as a positive control; the negative control was sterile H 2 O.

    Techniques: Sequencing